CNP (which stands for C-type natriuretic peptide) is a hormone that plays an important role in bone growth.
CNP activates the NPR-B receptors (natriuretic peptide receptor-B), reducing the effects of the overactive FGFR3 receptors which tell the bones to stop growing.
In clinical trials, scientists are studying the “decoy method” for achondroplasia.
Decoys are designed to block the molecules that normally activate the FGFR3 receptors.
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